{"id":1908,"date":"2023-10-19T02:01:01","date_gmt":"2023-10-18T18:01:01","guid":{"rendered":"https:\/\/lumistarbiotech.com\/?page_id=1908"},"modified":"2023-11-03T23:34:40","modified_gmt":"2023-11-03T15:34:40","slug":"science","status":"publish","type":"page","link":"https:\/\/lumistarbiotech.com\/ch\/science\/","title":{"rendered":"\u79d1\u5b78"},"content":{"rendered":"<div class=\"wp-block-uagb-container uagb-block-88609834 alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-container uagb-block-e1621e87\">\n<div class=\"wp-block-uagb-info-box uagb-block-f1477559 uagb-infobox__content-wrap  uagb-infobox-icon-above-title uagb-infobox-image-valign-top\"><div class=\"uagb-ifb-content\"><div class=\"uagb-ifb-title-wrap\"><span class=\"uagb-ifb-title-prefix\">Revolution<\/span><div class=\"uagb-ifb-separator\"><\/div><h1 class=\"uagb-ifb-title\">Induced Pluripotent Stem Cells (iPSC) Technology<\/h1><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-info-box uagb-block-8ffdb97e uagb-infobox__content-wrap  uagb-infobox-icon-above-title uagb-infobox-image-valign-top\"><div class=\"uagb-ifb-content\"><div class=\"uagb-ifb-title-wrap\"><\/div><p class=\"uagb-ifb-desc\">Induced pluripotent stem cell (iPSC) technology has the potential to transform the fields of drug discovery and cell therapy by providing a reliable<br>source of human cells for research and therapeutic purposes.<br>iPSCs can be differentiated into a wide range of cell types, allowing researchers to study disease mechanisms and test potential drug candidates in a<br>more physiologically relevant context. In addition, iPSCs can be used to generate organ-specific cells for use in cell therapies, which have the potential to treat a variety of diseases<\/p><\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-84f16a5f\">\n<div class=\"wp-block-uagb-container uagb-block-e1f42adc\"><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-be30c6b9\"><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-4247c971 alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-advanced-heading uagb-block-056fb1ad\"><h2 class=\"uagb-heading-text\">Application of iPSC<\/h2><\/div>\n\n\n\n<p>iPSCs are generated by reprogramming somatic cells, such as skin or blood cells, to an embryonic-like state through the forced expression of specific transcription factors. iPSCs have the capacity to differentiate into any cell type of the body, allowing for the creation of patient\/organ-specific cells that can be used to study disease mechanisms and develop new therapies.<\/p>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-f8a48132\">\n<div class=\"wp-block-uagb-info-box uagb-block-80b7d83a uagb-infobox__content-wrap  uagb-infobox-icon-above-title uagb-infobox-image-valign-top\"><div class=\"uagb-ifb-content\"><div class=\"uagb-ifb-image-content\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/lumistarbiotech.com\/wp-content\/uploads\/2023\/04\/drug_discovery2.png?resize=200%2C200&#038;ssl=1\" alt=\"\" width=\"200\" height=\"200\"\/><\/div><div class=\"uagb-ifb-title-wrap\"><h3 class=\"uagb-ifb-title\"><a href=\"#drug_discovery\">\u85e5\u7269\u958b\u767c<\/a><\/h3><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-info-box uagb-block-a5295084 uagb-infobox__content-wrap  uagb-infobox-icon-above-title uagb-infobox-image-valign-top\"><div class=\"uagb-ifb-content\"><div class=\"uagb-ifb-image-content\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/lumistarbiotech.com\/wp-content\/uploads\/2023\/04\/StemCell-Therapy-modified.png?resize=200%2C200&#038;ssl=1\" alt=\"\" width=\"200\" height=\"200\"\/><\/div><div class=\"uagb-ifb-title-wrap\"><h3 class=\"uagb-ifb-title\"><a href=\"#cell_therapy\">\u7d30\u80de\u6cbb\u7642<\/a><\/h3><\/div><\/div><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-168f6a45 alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-container uagb-block-c1b7846c\">\n<div class=\"wp-block-uagb-info-box uagb-block-925d0704 uagb-infobox__content-wrap  uagb-infobox-icon-above-title uagb-infobox-image-valign-top\" id=\"drug_discovery\"><div class=\"uagb-ifb-content\"><div class=\"uagb-ifb-title-wrap\"><span class=\"uagb-ifb-title-prefix\">Application of iPSC\u200b<\/span><div class=\"uagb-ifb-separator\"><\/div><h2 class=\"uagb-ifb-title\">\u85e5\u7269\u958b\u767c<\/h2><\/div><p class=\"uagb-ifb-desc\"><br>iPSC-derived cells can be used to create disease models by restoring disease phenotypes, either from patient samples or by CRISPR editing.<br>Researchers can generate iPSCs from patients with specific genetic mutations or disease phenotypes, and differentiate these cells into relevant cell<br>types such as cardiomyocytes, neurons, or liver cells. These cells are then used to study disease mechanisms, screen large libraries of compounds or drugs, and identify potential therapeutics that can restore normal function or alleviate disease symptoms.<\/p><\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-advanced-heading uagb-block-41dea53c\"><h5 class=\"uagb-heading-text\">Available Disease Models in LumiSTAR<\/h5><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Cardiac Disease Models<\/li>\n\n\n\n<li>Neurodegenerative Disease Models: Parkinson&#8217;s and Alzheimer&#8217;s Diseases<\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-6f37b74c\">\n<figure class=\"wp-block-image size-full is-resized\"><img data-recalc-dims=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/lumistarbiotech.com\/wp-content\/uploads\/2023\/10\/Drug_Discovery3.png?ssl=1\" alt=\"\" style=\"aspect-ratio:1.4431818181818181;width:483px;height:auto\"\/><\/figure>\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-bf4e5708 alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-container uagb-block-d7367a7d\">\n<div class=\"wp-block-uagb-info-box uagb-block-dd56f669 uagb-infobox__content-wrap  uagb-infobox-icon-above-title uagb-infobox-image-valign-top\" id=\"cell_therapy\"><div class=\"uagb-ifb-content\"><div class=\"uagb-ifb-title-wrap\"><span class=\"uagb-ifb-title-prefix\">Application of iPSC\u200b<\/span><div class=\"uagb-ifb-separator\"><\/div><h2 class=\"uagb-ifb-title\">\u7d30\u80de\u6cbb\u7642<\/h2><\/div><p class=\"uagb-ifb-desc\"><br>Induced pluripotent stem cells (iPSCs) can be used in cell therapy to treat various diseases or injuries by differentiating them into functional cells that<br>can replace or repair damaged cells or tissues, addressing unmet medical needs such as neurodegenerative disorders, spinal cord injuries, and kidney diseases (such as chronic kidney disease or acute kidney injury).<\/p><\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-advanced-heading uagb-block-96708586\"><h5 class=\"uagb-heading-text\">LumiSTAR&#8217;s Pipelines<\/h5><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Parkinson&#8217;s Disease<\/li>\n\n\n\n<li>Kidney Disease<\/li>\n\n\n\n<li>Cancer<\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-01d69ff0\">\n<div class=\"wp-block-uagb-image uagb-block-d76d4910 wp-block-uagb-image--layout-default wp-block-uagb-image--effect-static wp-block-uagb-image--align-none\"><figure class=\"wp-block-uagb-image__figure\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\"  sizes=\"auto, (max-width: 480px) 150px\" src=\"https:\/\/i0.wp.com\/lumistarbiotech.com\/wp-content\/uploads\/2023\/10\/363801737-vector-pdf.jpg?resize=413%2C374&#038;ssl=1\" alt=\"\" width=\"413\" height=\"374\" title=\"\"\/><\/figure><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-advanced-heading uagb-block-b4ca962d\"><h2 class=\"uagb-heading-text\">Pain Points on Developing Applications of iPSC Technology<\/h2><\/div>\n\n\n\n<p><\/p>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-cb9f1db4 alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-container uagb-block-a699e113\">\n<div class=\"wp-block-uagb-info-box uagb-block-bb3f2f81 uagb-infobox__content-wrap  uagb-infobox-icon-left uagb-infobox-left uagb-infobox-stacked-mobile uagb-infobox-image-valign-top\"><div class=\"uagb-ifb-icon-wrap\"><div class=\"uagb-iconbox-icon-wrap uagb-infobox-shape-circle\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 576 512\"><path d=\"M256 368C256 403.7 266.6 436.9 284.9 464.6L279.4 470.3C266.4 483.2 245.5 483.2 233.5 470.3L39.71 270.5C-16.22 212.5-13.23 116.6 49.7 62.68C103.6 15.73 186.5 24.72 236.5 75.67L256.4 96.64L275.4 75.67C325.4 24.72 407.3 15.73 463.2 62.68C506.1 100.1 520.7 157.6 507 208.7C484.3 198 458.8 192 432 192C334.8 192 256 270.8 256 368zM576 368C576 447.5 511.5 512 432 512C352.5 512 288 447.5 288 368C288 288.5 352.5 224 432 224C511.5 224 576 288.5 576 368zM476.7 324.7L416 385.4L387.3 356.7C381.1 350.4 370.9 350.4 364.7 356.7C358.4 362.9 358.4 373.1 364.7 379.3L404.7 419.3C410.9 425.6 421.1 425.6 427.3 419.3L499.3 347.3C505.6 341.1 505.6 330.9 499.3 324.7C493.1 318.4 482.9 318.4 476.7 324.7H476.7z\"><\/path><\/svg><\/div><\/div><div class=\"uagb-ifb-content\"><div class=\"uagb-ifb-title-wrap\"><h3 class=\"uagb-ifb-title\">Cell Maturity <\/h3><\/div><p class=\"uagb-ifb-desc\">Differentiated cells must reach a certain level of maturity to best reflect disease phenotype and be suitable for translation to cell therapy <\/p><\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-476b1ce8\">\n<div class=\"wp-block-uagb-info-box uagb-block-e947b896 uagb-infobox__content-wrap  uagb-infobox-icon-left uagb-infobox-left uagb-infobox-stacked-mobile uagb-infobox-image-valign-top\"><div class=\"uagb-ifb-icon-wrap\"><div class=\"uagb-iconbox-icon-wrap uagb-infobox-shape-circle\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 640 512\"><path d=\"M112 0C85.49 0 64 21.49 64 48V96H16C7.163 96 0 103.2 0 112C0 120.8 7.163 128 16 128H272C280.8 128 288 135.2 288 144C288 152.8 280.8 160 272 160H48C39.16 160 32 167.2 32 176C32 184.8 39.16 192 48 192H240C248.8 192 256 199.2 256 208C256 216.8 248.8 224 240 224H16C7.163 224 0 231.2 0 240C0 248.8 7.163 256 16 256H208C216.8 256 224 263.2 224 272C224 280.8 216.8 288 208 288H64V416C64 469 106.1 512 160 512C213 512 256 469 256 416H384C384 469 426.1 512 480 512C533 512 576 469 576 416H608C625.7 416 640 401.7 640 384C640 366.3 625.7 352 608 352V237.3C608 220.3 601.3 204 589.3 192L512 114.7C499.1 102.7 483.7 96 466.7 96H416V48C416 21.49 394.5 0 368 0H112zM544 237.3V256H416V160H466.7L544 237.3zM160 464C133.5 464 112 442.5 112 416C112 389.5 133.5 368 160 368C186.5 368 208 389.5 208 416C208 442.5 186.5 464 160 464zM528 416C528 442.5 506.5 464 480 464C453.5 464 432 442.5 432 416C432 389.5 453.5 368 480 368C506.5 368 528 389.5 528 416z\"><\/path><\/svg><\/div><\/div><div class=\"uagb-ifb-content\"><div class=\"uagb-ifb-title-wrap\"><h3 class=\"uagb-ifb-title\">High Throughput Screening<\/h3><\/div><p class=\"uagb-ifb-desc\">Advanced technologies are essential for efficient screening of iPSC-derived cells to gain more information on cellular functionality and drug response.<\/p><\/div><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-60d867fb alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-info-box uagb-block-44bb910a uagb-infobox__content-wrap  uagb-infobox-icon-above-title uagb-infobox-image-valign-top\"><div class=\"uagb-ifb-content\"><div class=\"uagb-ifb-title-wrap\"><span class=\"uagb-ifb-title-prefix\">OUR Solution<\/span><div class=\"uagb-ifb-separator\"><\/div><h2 class=\"uagb-ifb-title\">Integrating iPSCs with Live-Cell Bioimaging<\/h2><\/div><\/div><\/div>\n\n\n\n<p>LumiSTAR developed real-time detection technology (<a href=\"https:\/\/lumistarbiotech.com\/ch\/lumirdt\/\">LumiRDT<\/a>) based on genetically encoded tools, by which enables high-throughput screening of cellular functions for drug discovery and quality control of iPSC cell therapy.<\/p>\n\n\n\n<p>By visualizing and quantifying changes in cellular morphology, activities, and other cellular features, LumiSTAR\u2019s bio imaging platform can provide valuable insights into how drugs affect cells at the cellular level. In addition to drug discovery, bio imaging is also crucial for quality control in cell therapy. The success of iPS cell therapies relies on the maturation states of the cells to perform their intended functions in vivo. LumiSTAR\u2019s platform can be used to evaluate the quality and functionality of cells prior to their use in therapy. By assessing key cellular parameters mentioned above, LumiSTAR\u2019s system can help ensure the safety and efficacy of cell therapies.<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-uagb-advanced-heading uagb-block-688f95b1\"><h4 class=\"uagb-heading-text\">Advantages of <a href=\"http:\/\/lumistarbiotech.com\/ch\/lumirdt\/\">LumiRDT<\/a> (LumiSTAR Real-time Detection Technology)<\/h4><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-e8ef08b0\">\n<div class=\"wp-block-uagb-icon-list uagb-block-2052b811\"><div class=\"uagb-icon-list__wrap\">\n<div class=\"wp-block-uagb-icon-list-child uagb-block-e0329925\"><span class=\"uagb-icon-list__source-wrap\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 512 512\"><path d=\"M0 256C0 114.6 114.6 0 256 0C397.4 0 512 114.6 512 256C512 397.4 397.4 512 256 512C114.6 512 0 397.4 0 256zM371.8 211.8C382.7 200.9 382.7 183.1 371.8 172.2C360.9 161.3 343.1 161.3 332.2 172.2L224 280.4L179.8 236.2C168.9 225.3 151.1 225.3 140.2 236.2C129.3 247.1 129.3 264.9 140.2 275.8L204.2 339.8C215.1 350.7 232.9 350.7 243.8 339.8L371.8 211.8z\"><\/path><\/svg><\/span><span class=\"uagb-icon-list__label\">Non-toxic to cells<\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-icon-list-child uagb-block-ea9624c8\"><span class=\"uagb-icon-list__source-wrap\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 512 512\"><path d=\"M0 256C0 114.6 114.6 0 256 0C397.4 0 512 114.6 512 256C512 397.4 397.4 512 256 512C114.6 512 0 397.4 0 256zM371.8 211.8C382.7 200.9 382.7 183.1 371.8 172.2C360.9 161.3 343.1 161.3 332.2 172.2L224 280.4L179.8 236.2C168.9 225.3 151.1 225.3 140.2 236.2C129.3 247.1 129.3 264.9 140.2 275.8L204.2 339.8C215.1 350.7 232.9 350.7 243.8 339.8L371.8 211.8z\"><\/path><\/svg><\/span><span class=\"uagb-icon-list__label\">Allowing for long-term observations<\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-icon-list-child uagb-block-609315d8\"><span class=\"uagb-icon-list__source-wrap\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 512 512\"><path d=\"M0 256C0 114.6 114.6 0 256 0C397.4 0 512 114.6 512 256C512 397.4 397.4 512 256 512C114.6 512 0 397.4 0 256zM371.8 211.8C382.7 200.9 382.7 183.1 371.8 172.2C360.9 161.3 343.1 161.3 332.2 172.2L224 280.4L179.8 236.2C168.9 225.3 151.1 225.3 140.2 236.2C129.3 247.1 129.3 264.9 140.2 275.8L204.2 339.8C215.1 350.7 232.9 350.7 243.8 339.8L371.8 211.8z\"><\/path><\/svg><\/span><span class=\"uagb-icon-list__label\">Can be used in both 2D and 3D cell cultures\u200b<\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-icon-list-child uagb-block-ae0a69a1\"><span class=\"uagb-icon-list__source-wrap\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 512 512\"><path d=\"M0 256C0 114.6 114.6 0 256 0C397.4 0 512 114.6 512 256C512 397.4 397.4 512 256 512C114.6 512 0 397.4 0 256zM371.8 211.8C382.7 200.9 382.7 183.1 371.8 172.2C360.9 161.3 343.1 161.3 332.2 172.2L224 280.4L179.8 236.2C168.9 225.3 151.1 225.3 140.2 236.2C129.3 247.1 129.3 264.9 140.2 275.8L204.2 339.8C215.1 350.7 232.9 350.7 243.8 339.8L371.8 211.8z\"><\/path><\/svg><\/span><span class=\"uagb-icon-list__label\">Single cell detection is achievable<\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-icon-list-child uagb-block-8e44a211\"><span class=\"uagb-icon-list__source-wrap\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 512 512\"><path d=\"M0 256C0 114.6 114.6 0 256 0C397.4 0 512 114.6 512 256C512 397.4 397.4 512 256 512C114.6 512 0 397.4 0 256zM371.8 211.8C382.7 200.9 382.7 183.1 371.8 172.2C360.9 161.3 343.1 161.3 332.2 172.2L224 280.4L179.8 236.2C168.9 225.3 151.1 225.3 140.2 236.2C129.3 247.1 129.3 264.9 140.2 275.8L204.2 339.8C215.1 350.7 232.9 350.7 243.8 339.8L371.8 211.8z\"><\/path><\/svg><\/span><span class=\"uagb-icon-list__label\">Fluorescence imaging with a wide spectrum is available<\/span><\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-uagb-advanced-heading uagb-block-8481e1c4\"><h4 class=\"uagb-heading-text\">Advantages of LumiSTAR&#8217;s Imaging Platform<\/h4><\/div>\n\n\n\n<div class=\"wp-block-uagb-icon-list uagb-block-b958a101\"><div class=\"uagb-icon-list__wrap\">\n<div class=\"wp-block-uagb-icon-list-child uagb-block-ec559edc\"><span class=\"uagb-icon-list__source-wrap\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 512 512\"><path d=\"M0 256C0 114.6 114.6 0 256 0C397.4 0 512 114.6 512 256C512 397.4 397.4 512 256 512C114.6 512 0 397.4 0 256zM371.8 211.8C382.7 200.9 382.7 183.1 371.8 172.2C360.9 161.3 343.1 161.3 332.2 172.2L224 280.4L179.8 236.2C168.9 225.3 151.1 225.3 140.2 236.2C129.3 247.1 129.3 264.9 140.2 275.8L204.2 339.8C215.1 350.7 232.9 350.7 243.8 339.8L371.8 211.8z\"><\/path><\/svg><\/span><span class=\"uagb-icon-list__label\">Get instant response in real time for analysis<\/span><\/div>\n\n\n\n<div class=\"wp-block-uagb-icon-list-child uagb-block-9783234c\"><span class=\"uagb-icon-list__source-wrap\"><svg xmlns=\"https:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 512 512\"><path d=\"M0 256C0 114.6 114.6 0 256 0C397.4 0 512 114.6 512 256C512 397.4 397.4 512 256 512C114.6 512 0 397.4 0 256zM371.8 211.8C382.7 200.9 382.7 183.1 371.8 172.2C360.9 161.3 343.1 161.3 332.2 172.2L224 280.4L179.8 236.2C168.9 225.3 151.1 225.3 140.2 236.2C129.3 247.1 129.3 264.9 140.2 275.8L204.2 339.8C215.1 350.7 232.9 350.7 243.8 339.8L371.8 211.8z\"><\/path><\/svg><\/span><span class=\"uagb-icon-list__label\">Enable timely correction of developed protocols in cell differentiations, contributing to > 200 times faster in pipeline development<\/span><\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-4601f1df alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-container uagb-block-7f396ab7\">\n<div class=\"wp-block-uagb-info-box uagb-block-a6dcfa1f uagb-infobox__content-wrap  uagb-infobox-icon-above-title uagb-infobox-image-valign-top\"><div class=\"uagb-ifb-content\"><div class=\"uagb-ifb-title-wrap\"><span class=\"uagb-ifb-title-prefix\">How\u200b<\/span><div class=\"uagb-ifb-separator\"><\/div><h2 class=\"uagb-ifb-title\">Triple Core Technology<\/h2><\/div><\/div><\/div>\n\n\n\n<p>LumiSTAR\u2019s triple core technology platform represents a sophisticated combination of iPSCs, viral vectors, and genetically encoded tools that enable high throughput\/content screening for developing novel therapeutics<\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-testimonial uagb-slick-carousel uagb-tm__arrow-outside uagb-block-f8f6e096 uagb-post__carousel_notset uagb-post__carousel_notset-tablet uagb-post__carousel_notset-mobile\"><div class=\"is-carousel uagb-tm__columns-1 uagb-tm__items\"><div class=\"uagb-testimonial__wrap  uagb-tm__imgicon-style-circle uagb-tm__image-position-top uagb-tm__bg-type-color\"><div class=\"uagb-tm__content\"><div class=\"uagb-tm__overlay\"><\/div><div class=\"uagb-tm__image-content\"><div class=\"uagb-tm__image\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"uagb-tm-img-src\" src=\"https:\/\/i0.wp.com\/lumistarbiotech.com\/wp-content\/uploads\/2023\/03\/iPSC_icon.png?resize=80%2C80&#038;ssl=1\" alt=\"\" width=\"80\" height=\"80\"\/><\/div><\/div><div class=\"uagb-tm__text-wrap\"><div class=\"uagb-tm__desc\"><br>\u5206\u5316\u7d30\u80de\u53ef\u7528\u65bc\u85e5\u7269\u7814\u767c\u548c\u7d30\u80de\u6cbb\u7642<\/div><div class=\"uagb-tm__meta-inner\"><div class=\"uagb-testimonial-details\"><span class=\"uagb-tm__author-name\"><\/span><span class=\"uagb-tm__company\"><\/span><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-12f1e323\">\n<div class=\"wp-block-uagb-testimonial uagb-slick-carousel uagb-tm__arrow-outside uagb-block-58113c38 uagb-post__carousel_notset uagb-post__carousel_notset-tablet uagb-post__carousel_notset-mobile\"><div class=\"is-carousel uagb-tm__columns-1 uagb-tm__items\"><div class=\"uagb-testimonial__wrap  uagb-tm__imgicon-style-circle uagb-tm__image-position-top uagb-tm__bg-type-color\"><div class=\"uagb-tm__content\"><div class=\"uagb-tm__overlay\"><\/div><div class=\"uagb-tm__image-content\"><div class=\"uagb-tm__image\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"uagb-tm-img-src\" src=\"https:\/\/i0.wp.com\/lumistarbiotech.com\/wp-content\/uploads\/2023\/03\/protein.png?resize=80%2C80&#038;ssl=1\" alt=\"\" width=\"80\" height=\"80\"\/><\/div><\/div><div class=\"uagb-tm__text-wrap\"><div class=\"uagb-tm__desc\"><br>\u6d3b\u7d30\u80de\u5373\u6642\u751f\u7269\u5f71\u50cf\uff0c\u53ef\u5be6\u73fe\u9ad8\u5167\u6db5\u548c\u9ad8\u901a\u91cf\u7be9\u9078<\/div><div class=\"uagb-tm__meta-inner\"><div class=\"uagb-testimonial-details\"><span class=\"uagb-tm__author-name\">\u200b<\/span><span class=\"uagb-tm__company\"><\/span><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-testimonial uagb-slick-carousel uagb-tm__arrow-outside uagb-block-2bf63e2b uagb-post__carousel_notset uagb-post__carousel_notset-tablet uagb-post__carousel_notset-mobile\"><div class=\"is-carousel uagb-tm__columns-1 uagb-tm__items\"><div class=\"uagb-testimonial__wrap  uagb-tm__imgicon-style-circle uagb-tm__image-position-top uagb-tm__bg-type-color\"><div class=\"uagb-tm__content\"><div class=\"uagb-tm__overlay\"><\/div><div class=\"uagb-tm__image-content\"><div class=\"uagb-tm__image\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" class=\"uagb-tm-img-src\" src=\"https:\/\/i0.wp.com\/lumistarbiotech.com\/wp-content\/uploads\/2023\/03\/viral-vector.png?resize=80%2C80&#038;ssl=1\" alt=\"\" width=\"80\" height=\"80\"\/><\/div><\/div><div class=\"uagb-tm__text-wrap\"><div class=\"uagb-tm__desc\"><br>\u5728\u7d30\u80de\u5167\u5b89\u88dd\u57fa\u56e0\u7de8\u78bc\u5de5\u5177\uff0c\u4ee5\u4fbf\u9032\u884c\u6a19\u8a18\u3001\u6e2c\u91cf\u548c\u6cbb\u7642\u4e4b\u76ee\u7684<\/div><div class=\"uagb-tm__meta-inner\"><div class=\"uagb-testimonial-details\"><span class=\"uagb-tm__author-name\"><\/span><span class=\"uagb-tm__company\"><\/span><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-uagb-container uagb-block-8ff04f9b alignfull uagb-is-root-container\"><div class=\"uagb-container-inner-blocks-wrap\">\n<div class=\"wp-block-uagb-info-box uagb-block-1ce3292f uagb-infobox__content-wrap  uagb-infobox-icon-above-title uagb-infobox-image-valign-top\"><div class=\"uagb-ifb-content\"><div class=\"uagb-ifb-title-wrap\"><div class=\"uagb-ifb-separator\"><\/div><h2 class=\"uagb-ifb-title\"><br>Demonstration of Our Platform\u200b<\/h2><\/div><p class=\"uagb-ifb-desc\">High-Throughput Optical Controlling and Recording Calcium Signal in iPSC-Derived Cardiomyocytes for Toxicity Testing and Phenotypic Drug Screening<br><br><br>Chang, Y. F., Su, W. C., Su, C. C., Chung, M. W., Chang, J., Li, Y. Y., Kao, Y. J., Chen, W. P., Daniels, M. J. J. Vis. Exp. (181), e63175, doi:10.3791\/63175 (2022).<br><br><a href=\"https:\/\/www.jove.com\/t\/63175\/high-throughput-optical-controlling-recording-calcium-signal-ipsc\" target=\"_blank\" rel=\"noreferrer noopener\">Click<\/a><\/p><\/div><\/div>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Application of iPSC iPSCs are generated by reprogramming somatic cells, such as skin or blood cells, to an embryonic-like state through the forced expression of specific transcription factors. iPSCs have the capacity to differentiate into any cell type of the body, allowing for the creation of patient\/organ-specific cells that can be used to study disease [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-1908","page","type-page","status-publish","hentry"],"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"trp-custom-language-flag":false},"uagb_author_info":{"display_name":"MW","author_link":"https:\/\/lumistarbiotech.com\/ch\/author\/minwen-chung-chem\/"},"uagb_comment_info":0,"uagb_excerpt":"Application of iPSC iPSCs are generated by reprogramming somatic cells, such as skin or blood cells, to an embryonic-like state through the forced expression of specific transcription factors. iPSCs have the capacity to differentiate into any cell type of the body, allowing for the creation of patient\/organ-specific cells that can be used to study disease...","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/lumistarbiotech.com\/ch\/wp-json\/wp\/v2\/pages\/1908","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lumistarbiotech.com\/ch\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lumistarbiotech.com\/ch\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lumistarbiotech.com\/ch\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lumistarbiotech.com\/ch\/wp-json\/wp\/v2\/comments?post=1908"}],"version-history":[{"count":20,"href":"https:\/\/lumistarbiotech.com\/ch\/wp-json\/wp\/v2\/pages\/1908\/revisions"}],"predecessor-version":[{"id":2204,"href":"https:\/\/lumistarbiotech.com\/ch\/wp-json\/wp\/v2\/pages\/1908\/revisions\/2204"}],"wp:attachment":[{"href":"https:\/\/lumistarbiotech.com\/ch\/wp-json\/wp\/v2\/media?parent=1908"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}